Musculoskeletal Disorders

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Premature degenerative bone and joint disease in adults with DS is reported in the orthopaedic literature [Dacre and Huskisson, 1988; Olive et al., 1988]. Pain […]

Urinary Tract Disorders

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Recurrent urinary tract infections (UTIs) are of particular concern in our population. UTIs were documented in more than 25% of DS adults, particularly those who […]

Respiratory Tract Diseases

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Both acute and chronic problems of the respiratory tract occur frequently in our population. Three of the individuals with documented congenital heart anomalies also have […]

Hearing Disorders

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Recurrent and chronic ear infections in noncommunicative adults often go undiagnosed and can lead to mastoiditis and hearing loss. Almost half of the DS adults […]

Eye Disorders

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Previous reports confirm the high incidence of eye abnormalities in DS adults [Hestnes et al., 1991]. Normal ocular findings in DS adults are considered to […]

Health Care Concerns

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Frequently encountered and significant health concerns are summarised by organ system in Table II.-DISCUSSION Multiple health concerns are common in DS adults residing in Woodlands. […]

Deceased DS Adults

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Thirteen of 38 of our DS adults were deceased. The mean age of death was 48.5 years (range, 32–67 years). In the middle-aged group, 4/18 […]

Functional Health

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The decline in PCS scores in the middle decades of life was associated with an increase in the frequency of musculoskeletal complaints, particularly the symptoms […]